Norditropin Nordiflex Pen

Description

Buy NORDITROPIN NORDILET 10MG/1.5ML Online

Buy NORDITROPIN NORDILET 10MG is a synthetic human growth hormone, prescribed for growth hormone deficiency and turner syndrome. It works by stimulating growth in patients who do not make enough natural growth hormone.

Norditropin Nordilet Injection works by increasing the production of protein in the body.

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Posology NORDITROPIN NORDILET 10MG

The dosage of NORDITROPIN NORDILET 10MG is individual and must always be adjusted in accordance with the individual’s clinical and biochemical response to therapy.

Generally recommended dosages:

Paediatric population:

Growth hormone insufficiency

0.025-0.035 mg/kg/day or 0.7-1.0 mg/m²/day

When GHD persists after growth completion, growth hormone treatment should be continued to achieve full somatic adult development including lean body mass and bone mineral accrual.

Turner syndrome

0.045-0.067 mg/kg/day or 1.3-2.0 mg/m²/day

Chronic renal disease

0.050 mg/kg/day or 1.4 mg/m²/day

Small for Gestational Age

0.035 mg/kg/day or 1.0 mg/m²/day

A dose of 0.035 mg/kg/day is usually recommended until final height is reached. Treatment should be discontinued after the first year of treatment, if the height velocity SDS is below +1.

Treatment should be discontinued if height velocity is < 2 cm/year and, if confirmation is required, bone age is > 14 years (girls) or > 16 years (boys), corresponding to closure of the epiphyseal growth plates.

Adult population:

Replacement therapy in adults

The dosage must be adjusted to the need of the individual patient.

In patients with childhood onset GHD, the recommended dose to restart is 0.2-0.5 mg/day with subsequent dose adjustment on the basis of IGF-I concentration determination.

In patients with adult onset GHD, it is recommended to start treatment with a low dose: 0.1- 0.3 mg/day. It is recommended to increase the dosage gradually at monthly intervals based on the clinical response and the patient’s experience of adverse events. Serum IGF-I can be used as guidance for the dose titration. Women may require higher doses than men, with men showing an increasing IGF-I sensitivity over time. This means that there is a risk that women, especially those on oral oestrogen replacement are under-treated while men are over-treated.

Dose requirements decline with age. Maintenance dosages vary considerably from person to person, but seldom exceed 1.0 mg/day.

Method of administration

Generally, daily subcutaneous administration in the evening is recommended. The injection site should be varied to prevent lipoatrophy.

Side effects NORDITROPIN NORDILET 10MG

Buy NORDITROPIN NORDILET 10MG can cause side effects. The following important adverse reactions are also described elsewhere in the labeling:

• Increased mortality in patients with acute critical illness
• Sudden death in children with Prader-Willi syndrome
• Neoplasms
• Glucose intolerance and diabetes mellitus
• Intracranial hypertension
• Severe hypersensitivity